Objective: To evaluate the supplementation effects of vitamin E, vitamin C, superoxide dismutase (SOD), and catalase to ......

LncRNA在真核生物中广泛转录,且响应于细胞外环境的变化.相比于mRNA,人们对lncRNA在DNA损伤应答中的作用了解甚少.基于高通量测序,......

Objective:Autophagy is a programmed cell death procedure,which has essential functions in tumorigenesis.However,its temp......

环状RNA （CircRNA）是一类由外显子、内含子或基因间区经反向剪接形成的非编码RNA，具有种类丰富、序列保守、结构稳定和细胞组织特异性......

Purinergic receptors have been reported to be involved in brain disorders.In this study,we explored their roles and mech......

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This study was conducted to clarify the toxic effects of sertraline (SRT) on the reproductive system of male rats and to......

Sperm DNA damage is recognized as an important biomarker of male infertility. To investigate this, sperm DNA damage was ......

Sperm are a highly specialized cell type derived to deliver the paternal haploid genome to the oocyte. The epigenetic,or......

The sperm nucleus is prone to sustain DNA damage before and after ejaculation.Distribution of the damage is not homogene......

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A cross-sectional study was conducted on a total of 584 exposed subjects and 138 controls in an electronics factory.We e......

Objective: To study the preventive effect of Total Codonopsis lanceolata Saponin (CLS) on the damage of liver cell DNA i......

DNA-damaging agents have been reported to be associated with cardiovascular complications;however, the underlying mechan......

Integrity of both nuclear and mitochondrial DNA is vital for the survival of an organism.Exposure to genotoxic agents ha......

The potential application of gold nanoparticles(GNPs)as radiosensitizers in cancer radiotherapy attracts considerate int......

In radiotherapy,ionizing photons or particles deliver their energy in cells by the formation of tracks composed of small......

The antioxidant activities of the soluble eggshell membrane protein (SEP) and its peptides were investigated by using a ......

Objective:This study was designed to exploit the cytotoxic effects of both cobalt nanoparticles and ions on human periph......

Objective To investigate the relationship between DNA damage which was considered enhancing apoptosis and metabolites af......

Objective: Although the cytoxicity induced by Cobalt ions (Co2+) and nanoparticles (Co-NPs) which released from the tota......

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Objective Defects of DNA damage response(DDR)will result in genome instability and drive carcinogenesis.Proteins carryin......

目的 Cyclin dependent kinase 1 (CDK1) is an essential kinase that involves in a wide range of biological processes which......

ALDH2 is a member of aldehyde dehydrogenase superfamily that implicates in metabolic processes of aldehydes.ALDH2 plays ......

Objective: To study the effects of Astragalus Polysaccharide(APS) on the proliferation level and the protective effect o......

Purpose To investigate the mechanisms of adriamycin(ADR)for proliferative vitreoretinopathy(PVR)treatment by using human......

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The accurate segregation of chromosomes during cell division is essential to secure the propagation of normal cells, and......

AIM: To investigate the role of miR-16 in the process of DNA damage protection by resveratrol on colon epithelial cells.......

Objective Millions of patients worldwide are suffered from Parkinsons disease(PD),a complex chronic neurodegenerative di......

Aim: One major pathological hallmark of Alzheimers disease (AD) is the aggregation of amyloid beta-peptide (Aβ), which ......

Aim: RPA2 is a subunit of a trimeric RPA complex important for DNA repair and replication.Although it is known that RPA ......

Aim: Cucurbitacin B (Cuc B), a natural triterpenoid with potent anti-cancer activities both in vitro and in vive, induce......

[Au(L)Cl2](1)with pyridine-2-carboxylic acid(2-benzo[1,3]dioxol-5-yl-ethyl)-amide(H–L)were synthesized and characterize......

Background,aim,and scope It has been known that the pollutants of e-wastes can lead to severe pollution to the environme......

Cucurbitacin B (Cuc B), a tetracyclic triterpene, is an extract from cucurbitaceous plants and has been demonstrated pos......

Down-regulation of hSSB 1, a single-stranded DNA-binding protein, causes increased radiosensitivity, defective checkpoin......

OBJECTIVE Reactive oxygen species (ROS) mediated both apoptosis and protective autophagy in response to natural products......

Objective: To investigate the effects of electromagnetic pulses (EMP) on cell viability, DNA damage, expression of heat ......

Background,aim,and scope Electronic wastes (e-wastes) are being the fastest growing type of solid waste.Most of them wer......

Objective Long-term excessive sodium fluoride (NaF) intake can cause many bone diseases and non-skeletal fluorosis.The k......

To overcome the serious chemo-resistant phenotype of the advanced cancers,it is urgently required to precisely understan......

Ubiquitin linkage is critical in directing the cellular fate of a ubiquitinated protein.Although K48-linked polyubiquiti......